Perfectly Green Organocatalysis: Quaternary Ammonium Base Triggered Cyanosilylation of Aldehydes
发表时间：2019-03-09
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- 论文类型：
- 期刊论文
- 第一作者：
- Wen Yeqian
- 通讯作者：
- Wang, YM (reprint author), Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Liaoning, Peoples R China.
- 合写作者：
- Liang Mengwei,Wang Yiming,Ren Weimin,Lu Xiaobing
- 发表时间：
- 2012-09-01
- 发表刊物：
- CHINESE JOURNAL OF CHEMISTRY
- 收录刊物：
- SCIE、Scopus
- 文献类型：
- J
- 卷号：
- 30
- 期号：
- 9,SI
- 页面范围：
- 2109-2114
- ISSN号：
- 1001-604X
- 关键字：
- organocatalysis; green chemistry; cyanosilylation; quaternary ammonium base; solvent-free
- 摘要：
- Quaternary ammonium bases, such as aqueous (CH3)4NOH, were found to be an extraordinarily efficient catalyst for cyanosilylation of aldehydes. The addition reaction of trimethylsilyl cyanide (TMSCN) to equivalent aldehydes could proceed smoothly with turnover frequency (TOF) up to 3000000 h-1 and in near 100% yield under solvent-free conditions. These organic catalysts also tolerated various aldehydes including aromatic, aliphatic and a,beta-unsaturated aldehydes. This process perfectly conforms to the features of green chemistry: no waste regarding side-products and unconverted reactants, solvent-free, excellent catalytic activity, and no requirement for separation.
- 是否译文：
- 否
