Improvements of Corrosion Resistance and Antibacterial Properties of Hydroxyapatite/Cupric Oxide Doped Titania Composite Coatings on Degradable Magnesium Alloys
发布时间：2026-01-13
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- 论文类型：
- 期刊论文
- 发表时间：
- 2020-11-10
- 发表刊物：
- Langmuir
- 收录刊物：
- SCI
- 文献类型：
- J
- 卷号：
- 36
- 期号：
- 46
- 页面范围：
- 13937-13948
- ISSN号：
- 0743-7463
- 关键字：
- Alloys, Coating materials, Composites, Electrochemistry, Oxidation
- 摘要：
- The excellent biocompatibility of calcium phosphate (CaP) coatings makes them widely used in magnesium (Mg) alloy orthopedic implant materials. However, the porous morphology of CaP coatings limits their corrosion resistance. A cupric oxide (CuO) doped titania (TiO2) sol–gel coating is prepared on a porous hydroxyapatite (HA) coating. According to electrochemical test results, the HA/CuO–TiO2 coating obtains a current density of 6 × 10–4 mA/cm2, lower than that of the Mg alloy (2.6 × 10–2 mA/cm2). The hydrogen evaluation of the HA/CuO–TiO2 coating is only 1/12 that of the Mg alloy after immersion for 7 days. In addition, the HA/CuO–TiO2 coating has an antibacterial rate of 99.5 ± 0.4% against Staphylococcus aureus, significantly higher than that of the HA coating (19.8 ± 0.3%) and HTC0 coating (38.4 ± 0.5%). The CuO doped composite coating has no adverse effect or cytotoxicity on cell proliferation (cell viability ≥79.6%). Hence, the HA/CuO–TiO2 composite coating is useful for enhancing the corrosion resistance and antibacterial properties of Mg alloys while ensuring cytocompatibility. The HA/CuO–TiO2 coated AZ60 Mg alloy can meet the requirements of clinical application.
- DOI码：
- 10.1021/acs.langmuir.0c02442
- 影响因子：
- 3.9
- 第一作者
- Yingchao Xu
- 合写作者
- 王天笑,Jianshe Lian
- 通讯作者
- Yunting Guo,Guangyu Li