大连理工大学主页平台管理系统 Chemical Biology Research Group--Home-- 3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile (S1) Based Molecules as Potent, Dual Inhibitors of B-Cell Lymphoma 2 (Bcl-2) and Myeloid Cell Leukemia Sequence 1 (Mcl-1):

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A novel BH3 mimetic S1 potently induces Bax/Bak-dependent apoptosis by targeting both Bcl-2 and Mcl-1.

An Anthraquinone Scaffold for Putative, Two-Face Bim BH3 α-Helix Mimicries.

3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile (S1) Based Molecules as Potent, Dual Inhibitors of B-Cell Lymphoma 2 (Bcl-2) and Myeloid Cell Leukemia Sequence 1 (Mcl-1):

Release time:2019-03-12 Hits:

Indexed by: 期刊论文

First Author: 张志超

Date of Publication: 2011-01-01

Journal: JMC

Document Type: J

Volume: 54

Issue: 127

Page Number: 1101-1105

Translation or Not: no